What Is NAD Infusion?
A NAD infusion delivers NAD+ directly into your bloodstream through an IV. To see why people get one, it helps to know what NAD does. NAD is short for nicotinamide adenine dinucleotide, a molecule found in every cell in your body. It helps turn the food you eat into usable energy, repair DNA and protect your cells from stress. NAD exists in two forms, NAD+ and NADH, which pass electrons back and forth like a shuttle inside your cells. NAD+ is the form used in infusions.
Your NAD levels do not stay steady for life. Research shows that aging brings a gradual decline in NAD+ levels, and that decline is linked to many age-related changes. That is the idea behind NAD therapy: restore what your body is running low on.
An IV sends NAD straight into a vein, usually in your arm, so it bypasses your digestive system entirely. This is why many people choose an infusion over oral supplements.
NAD Injection vs. NAD IV Infusion
NAD can be given two ways, and the right one depends on your goal, your schedule and how your body responds.
NAD Injection
A NAD injection, also called a NAD+ shot, is a small dose given into a muscle or under the skin. It takes only a few minutes, so it suits people who want a quicker visit or a smaller maintenance dose between infusions. Injections can also work well if sitting for a long infusion is hard for you.
NAD IV Infusion
A NAD IV infusion drips a larger dose into your vein over a few hours. The slow drip lets your body take in more NAD than a shot, and the rate can be adjusted if you feel any discomfort. Most people start with infusions and use injections later for maintenance.
NAD+ Infusion cost ranges from $125 – $500 at Renew Integrative Health Clinic in Newark, DE
When thinking about an NAD+ infusion, it is helpful to know about the cost. At Renew Integrative Health Clinic in Newark, DE, the price ranges between $125 and $500. The price depends on the amount of NAD you receive and how long the infusion takes. NAD+ injections usually cost less per visit, while IV infusions deliver a larger dose.
NAD infusion therapy is considered an elective wellness treatment, so insurance will likely not cover it. If you plan a series of sessions, ask about package options during your consultation so you know the full cost up front. Your consultation covers the dose and number of sessions that fit your goals, so your estimate is specific to you.
Benefits of NAD+ Infusions and Injections
Most NAD benefits come from its role in cellular energy and repair. Human research on IV NAD is still early, so here is what the evidence supports and where it is still developing.
Cellular Energy
NAD is central to how your cells turn food into energy. When levels run low, restoring them may help you feel less tired. Many patients report more energy after a series of infusions, although controlled trials of IV NAD are still limited.
Focus and Brain Fog
NAD supports brain cells and the energy they need to communicate. People often report clearer thinking after an infusion. NAD’s role in brain aging is an active area of research, including studies in Parkinson’s and Alzheimer’s disease.
Exercise Recovery
Muscles use a lot of energy during and after exercise. More available NAD may support stamina and recovery, though most of this evidence comes from lab and animal studies. If recovery is your goal, protein, sleep and a sensible training load matter more than any single infusion.
Healthy Aging
Because NAD helps repair DNA and keeps cells working well, restoring it is being studied as a way to support healthy aging. Researchers note that much remains to be learned about how NAD+ affects human health, so treat this as promising rather than proven. The lifestyle habits that support NAD, covered in the FAQs below, work alongside any infusion.
Watch in this youtube short reel the success story of a current patient Donna’s testimonial 2 days after recieving her NAD+ infusion at Renew Integrative Health. Subscribe to our youtube for videos to learn more about functional medicine.
Metabolism and Insulin Sensitivity
A review of clinical trials found that NADH supplementation was linked to improved insulin sensitivity, lower anxiety and better quality of life in some studies. These trials mostly used NADH by mouth, so results may not carry over directly to IV NAD.
Does NAD IV Actually Work?
It depends on what you expect from it. NAD clearly matters for energy and repair, and levels clearly fall with age. What is still missing is large human trials showing that IV NAD improves specific health outcomes. Many patients feel a real difference, and the best way to judge is a defined goal and an honest check-in after a few sessions.
What Is NAD Therapy Used For?
NAD+ infusions are used as a supportive therapy, not a cure. In functional medicine, people most often use NAD for:
- Low energy and fatigue
- Brain fog and trouble concentrating
- Exercise recovery
- Healthy aging
- Support during recovery from alcohol or substance use
- Fibromyalgia and chronic fatigue syndrome
Clinical studies have also looked at NAD in chronic fatigue syndrome, Parkinson’s and Alzheimer’s disease. Evidence for most of these uses is still developing, which is why NAD therapy works best as one part of a wider plan.
NAD Infusion Side Effects
Most NAD infusion side effects are mild and happen during the drip. A 2026 study of IV NAD+ found that some people felt stomach upset, a faster heart rate or chest pressure during the infusion. Slowing the drip helped, and symptoms faded once the infusion ended.
Other effects can include:
- Discomfort or bruising where the IV goes in
- Flushing, warmth or lightheadedness
- Nausea or cramping
- A mild headache or tiredness after the session
This is why a nurse adjusts your drip rate and checks on you throughout. Tell your provider about any heart condition before your first infusion.
Who Is a Good Candidate for NAD Therapy?
NAD therapy tends to suit adults who have a clear goal, such as more energy, sharper focus or better recovery, and who want to support those goals alongside sleep, nutrition and exercise. It is not a replacement for finding the root cause of fatigue or brain fog.
Talk with your provider first if you are pregnant or breastfeeding, have a heart or kidney condition, or take several medications. Your health history and current symptoms guide whether an infusion, injections or a different approach makes the most sense for you.
What to Expect During NAD Infusion Therapy
NAD infusions usually take 2 to 6 hours, depending on your dose and how quickly your body tolerates the drip. Here is what a typical appointment looks like.
First, you settle into a comfortable reclining chair. A nurse places a small IV in a vein in your arm, which may feel like a quick pinch. The nurse then connects the bag of NAD solution and starts a slow drip. While it runs, you can read, watch a show or relax. We provide internet access, Netflix, a large book selection, snacks and herbal teas.
The nurse checks on you often and slows the drip if you feel any discomfort. When the infusion is done, the IV comes out and you get a small bandage. Most people return to their regular day right after.
For a real-life look, watch the video at the top of this page.
How to Prepare for Your NAD+ Infusion Appointment
Getting ready for your NAD+ infusion is easy.
- Drink water. Being well hydrated makes it easier for the nurse to find a vein.
- Eat something. A small meal or snack beforehand helps you feel steady during the drip.
- Wear comfy clothes. Choose loose sleeves you can push up, since you will be seated for a while.
- Bring something to do. A book, headphones or a tablet makes the time go quickly.
NAD IV Infusion FAQs
Is NAD+ IV Infusion Safe?
For most people, NAD+ infusions are well tolerated when a trained professional gives them and adjusts the drip rate. A review of clinical trials found that NADH has a low rate of side effects, none of them serious. Long-term data on IV NAD is still limited, so your health history is reviewed before you start.
How Long Does NAD+ Infusion Take?
An infusion usually takes 2 to 6 hours. The time depends on your dose and how quickly your body tolerates the drip.
How Often Should You Get NAD IV Therapy?
There is no single schedule. Many people start with a short series of infusions over a few weeks, then move to maintenance sessions or injections spaced further apart. Your plan is based on your goals and how you respond. Our holistic medicine practitioner, Andrea Dean, CRNP, can help you decide on the right schedule.
How Long Do NAD Infusion Effects Last?
NAD+ leaves your bloodstream quickly. A pilot study found it was cleared from plasma within the first hours of an infusion as your cells take it up. How long you feel the benefits varies from person to person, which is why follow-up visits help fine-tune your schedule.
Is NAD Like Ozempic?
No. NAD+ is a molecule your cells use for energy and repair. Ozempic is an FDA-approved GLP-1 medication for type 2 diabetes. NAD+ is not an approved weight-loss treatment, although supporting your metabolism is one reason people use it.
NAD IV vs. NAD Supplements: Which Is Better?
Oral NAD supplements are convenient, but how well your body absorbs them is still being studied. Research on NAD+ supplements is ongoing. An IV bypasses digestion and delivers a known dose, which is why many people choose infusions for a faster, more direct effect.
Can I Boost NAD Levels Naturally?
Yes. Foods rich in vitamin B3 and tryptophan, such as meat, fish, legumes, nuts, eggs and dairy, help your body make NAD. Regular exercise, good sleep, stress management and limiting alcohol also help. Some people make these changes and still feel depleted, and that is when an infusion may be worth discussing.
Looking for NAD IV Therapy in Newark, DE?
If you are searching for NAD IV therapy near me in Delaware, Renew Integrative Health in Newark offers NAD infusions and injections in a comfortable, relaxed setting. Book a consultation with our nurse practitioner to talk through your goals, review your health history and find out whether NAD therapy is a good fit.
Blog Posts
Check out our latest post on NAD IV therapy: Five Ways NAD IV Therapy Can Help Reverse Aging